Lymphoma Series: Variants of Large-Cell Lymphoma

Correspondence: Ann S. LaCasce, M.D., Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA. Telephone: 617-632-5959 Fax: 617-632-5890; e-mail: [email protected] Received March 20, 2006; accepted for publication April 11, 2006. ©AlphaMed Press 1083-7159/2006/$20.00/0 Abstract Post-transplant lymphoproliferative disorder is the most common malignancy, with the exception of skin cancer, after solid organ transplantation in adults. The incidence varies according to the transplanted organ and is often associated with Epstein-Barr virus. Prognosis is variable, due in part to the heterogeneity of the disease, which ranges from reactive plasmacytic hyperplasia to aggressive monoclonal disease. The Oncologist 2006;11:674–680